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Slay The Spire – How to Start an Endless Mode Run

Jan 28, 2026
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In this short video we show exactly how to start Endless Mode in Slay The Spire and what to expect. You will learn how to unlock the Custom Game option (complete a Daily Climb), where to find Endless Mode in the custom menu, how to pick modifiers and character, hit Embark, and what the infinity symbol and Blights mean when you play repeated runs. This quick walk-through is made for players who want to try Endless Mode fast and with no confusion. How to start Endless Mode in Slay The Spire? How to unlock Custom Game and Endless Mode in Slay The Spire? What does Endless Mode do in Slay The Spire and how does the Blight system work? 0:00 Intro — What Endless Mode is and quick overview 0:05 Unlock Custom Game — Complete a Daily Climb to enable it 0:23 Customize run — Pick modifiers, ascension, and character 0:30 Find Endless Mode — Locate it (about 4th option from top) 0:47 Choose settings & hit Embark — Start the Endless run 1:12 Infinity icon — See the infinity symbol next to your name 1:19 Map note & behavior — Winning, returning to Act 1, and Blights 1:27 Outro — Abandoning the run and final tips #SlayTheSpire #EndlessMode #SlayTheSpireEndless #GamingTips Find out more: https://www.hardreset.info/devices/game/game-slay-the-spire/

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